
Non-invasive solution
This treatment uses botulinum toxin type E (trenibotulinumtoxinE), a new generation of wrinkle relaxer designed to deliver faster results with a shorter duration of effect. It works by temporarily relaxing the muscles responsible for frown lines between the eyebrows, helping to smooth their appearance. Unlike traditional neurotoxins, which typically take several days to begin showing results and last three to four months, this treatment can produce visible improvements within hours, with results generally lasting two to three weeks.
Its shorter duration makes it particularly appealing to those who are curious about neuromodulators but hesitant to commit to several months of results. Whether you're unsure how you'll like the look or feel of relaxed facial muscles, or simply prefer a more temporary option, this treatment offers an opportunity to experience the effects of wrinkle relaxers before considering a longer-lasting alternative. The procedure itself takes just a few minutes, with no downtime typically required.
First time neurotoxin client received botulinum toxin type E injections to the glabellar region for rapid result.
Botulinum toxin type E injected into the glabellar region for rapid-onset and short duration smoothing of “11” lines.
Photos courtesy of Victoria Park Medispa.
Warning: These photos are published for reference only to provide information on the nature of the treatment.
They do not constitute a guarantee of results.
Frown lines form when the muscles between your eyebrows contract as you frown, squint or concentrate. Over time, these repeated expressions can cause lines to become more noticeable, even when your face is relaxed.
This treatment temporarily reduces the movement of these muscles, allowing the skin above them to appear smoother and more relaxed. By softening the muscle contractions responsible for frown lines, it helps create a refreshed appearance without changing your natural facial features.
Botulinum toxin type E injections are postponed during pregnancy or breastfeeding.
Any active skin condition in the treatment area, such as a rash, irritation, inflammation, herpes outbreak, or open wound, must be fully resolved before the session.
Certain neuromuscular disorders or a known allergy to botulinum toxin require prior medical evaluation.
The use of anticoagulants or medications affecting blood clotting should also be discussed.
Got questions about botulinum toxin type ? We’ve got your answers here!
This treatment may be suitable for adults with moderate to severe frown lines between the eyebrows, particularly those who:
-Are considering neuromodulators for the first time and want to experience the results before committing to a longer-lasting treatment
-Are curious about wrinkle relaxers but unsure how they will like the appearance or sensation of relaxed facial muscles
-Have hesitated to try traditional neuromodulators because their effects cannot be immediately reversed
-Prefer a shorter duration of results
Your injector will assess your medical history, facial anatomy and aesthetic goals to determine whether this treatment is appropriate for you.
Consultation fees and treatment costs vary depending on the clinic, the provider, and the recommended treatment plan.
Visible improvements may begin to appear in as little as eight hours after treatment. Results continue to develop over the following days, with the peak effect typically visible within one week.
This treatment is designed to temporarily relax the muscles responsible for frown lines, helping to soften their appearance without necessarily eliminating all facial expression.
This treatment is designed to soften frown lines while maintaining a natural-looking appearance. In a 2026 clinical study published in Aesthetic Surgery Journal, approximately 85% of treated participants were satisfied with how natural their results looked after seven days.
Your injector will assess your facial anatomy, muscle movement and aesthetic goals to determine the most appropriate treatment approach.
Results typically last two to three weeks, compared to approximately three to four months with traditional neuromodulators. This shorter duration makes the treatment an appealing option for those who prefer temporary results or want to experience the effects of wrinkle relaxers before committing to a longer-lasting treatment.
Yes. For patients who are new to wrinkle relaxers, this treatment offers an opportunity to experience the results before considering a longer-lasting option.
If you're happy with the outcome, your injector can discuss transitioning to a traditional neuromodulator and recommend an appropriate timeline for your next treatment.
Yes, botulinum toxin type E has been evaluated in clinical studies and is approved by Health Canada for specific cosmetic indications. As with other neuromodulators, side effects may include temporary redness, swelling, bruising or tenderness at the injection site.
Your injector will review your medical history and any potential risks before treatment to determine whether it is appropriate for you.
This treatment is currently approved in Canada for the temporary improvement of moderate to severe frown lines between the eyebrows, also known as glabellar lines.
If you are interested in treating other areas, such as forehead lines or crow's feet, your injector can recommend an appropriate alternative.
There is typically no downtime required, and most patients can return to their regular daily activities immediately after their appointment.
You may experience mild redness, swelling or tenderness around the injection sites, which generally resolves on its own. Your injector will provide specific aftercare instructions to help ensure the best possible results.
Touch-ups are not routinely recommended with this treatment. Because results develop quickly and typically last only two to three weeks, additional injections during the same treatment cycle are generally unnecessary.
Your injector can assess your results and recommend any adjustments for future treatments.
Depending on your aesthetic goals, this treatment may be incorporated into a personalized treatment plan alongside other injectable or skin rejuvenation treatments.
Your provider will assess which treatments are appropriate to combine and whether they should be performed during the same appointment or scheduled separately.
The primary difference is the onset and duration of results. This treatment uses botulinum toxin type E, which acts more quickly and has a shorter duration of effect than the botulinum toxin type A used in most traditional neuromodulators.
While traditional treatments generally last three to four months, the effects of botulinum toxin type E typically fade within two to three weeks. This offers a shorter-term option for those who are new to wrinkle relaxers or prefer a more temporary result.
Our partnership with Beautifi means our patients can get the treatments they deserve with low-interest, flexible monthly payments.
If you discover a better price on laser-based aesthetic services, let us know, and we’ll match that figure.*Details apply.
Our medical team is made up of the country’s top board-certified plastic surgeons and dermatologists. These experts are supported by a team of dedicated registered nurses who are passionate about helping you achieve your aspirations.
Not sure which treatment is right for you? Schedule a consultation with one of our experts today.
Not ready to book your consultation yet? Contact us by filling in the form below or call us at 1-(833)-488-8668 to discuss your questions with a member of our Appointment Concierge Team. We look forward to helping you.